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Narcolepsy Sleep Disorder

Narcolepsy affects an estimated 250,000 Americans. People with narcolepsy suffer frequent "sleep attacks" during the day, even if they enjoy a normal amount of night-time sleep. These attacks can last anything from several seconds to more than 30 minutes.

People with narcolepsy may also experience cataplexy (loss of muscle control during emotional situations), hallucinations, temporary paralysis when they awaken, and disrupted night-time sleep. These symptoms seem to be features of REM sleep that appear during waking, which suggests that narcolepsy is a disorder of sleep regulation.

The symptoms of narcolepsy typically appear during adolescence, though it often takes years to obtain a correct diagnosis.

The disorder (or at least a predisposition to it) is usually hereditary, but it is occasionally linked to brain damage from a head injury or to neurological disease.

Once diagnosed, stimulants, antidepressants, or other drugs can help control the symptoms and prevent the embarrassing and dangerous effects of falling asleep at improper times. Naps at certain times of the day may also reduce the excessive daytime sleepiness.

In 1999, a research team working with canine models identified a gene that causes narcolepsy - a breakthrough that brings a cure for this disabling condition within reach.

The gene, hypocretin receptor 2, codes for a protein that allows brain cells to receive instructions from other cells. The defective versions of the gene encode proteins that cannot recognize these messages, perhaps cutting the cells off from messages that promote wakefulness.

The researchers know that the same gene exists in humans, and they are currently searching for defective versions in people with narcolepsy.

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narcolepsy - Google News

Jimmy Kimmel has narcolepsy - Celebrities With Diseases
10 Mar 2010 at 5:17pm

Celebrities With Diseases

Jimmy Kimmel has narcolepsy
Celebrities With Diseases
Late-night TV host and comedian Jimmy Kimmel has been very open about his struggle with narcolepsy - a neurological condition whereby the sufferer ...


 
What is narcolepsy? - Celebrities With Diseases
8 Mar 2010 at 2:52pm

What is narcolepsy?
Celebrities With Diseases
As many as 200000 Americans suffer from narcolepsy, although fewer than 50000 are diagnosed, according to Med TV. Narcolepsy is a disorder affecting the ...


 
Researchers find trigger for narcolepsy: study - AFP
17 Feb 2010 at 10:46am

AFP

Researchers find trigger for narcolepsy: study
AFP
GENEVA ? Swiss scientists say they have found a trigger for narcolepsy, the health disorder that sparks sudden daytime bouts of tiredness or sleep, ...
Narcolepsy may be autoimmune disorderUPI.com
Researchers find cause of narcolepsyWorld Radio Sw...

 
Fainting Spells - New York Times
26 Feb 2010 at 11:39pm

New York Times

Fainting Spells
New York Times
What she probably had, Ledereich told her, was something called cataplexy, and that meant that she also had narcolepsy. With narcolepsy, elements of sleep ...

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The information contained here should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The information provided here is for educational and informational purposes only and in no way should be considered as an offering of medical advice.